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Autism Is Like Mercury Poisoning

Autism Mimics The Exact Same Symptoms As Mercury Poisoning!

In this article you will see that autism, considered virtually an incurable disease, may well be nothing more than mercury poisoning -- and Life Glow Plus oral chelation should handle this completely.


by
Sallie Bernard*  
Albert Enayati, B.S., Ch.E., M.S.M.E.**  
Heidi Roger  
Teresa Binstock  
Lyn Redwood, R.N., M.S.N., C.R.N.P.  
Woody McGinnis, M.D.

    *Contact:        sbernard@nac.net 

  ã2000 by ARC Research  
14 Commerce Drive  
Cranford, NJ 07016  
April 3, 2000


ABSTRACT  

Autism is a neurodevelopmental syndrome characterized by impairments in social relatedness, language, and communication, a need for routine and sameness, abnormal movements, and sensory dysfunction.  Mercury is a toxic metal that can exist as a pure element or in a variety of inorganic and organic forms and can cause immune, sensory, neurological, motor, and other behavioral dysfunctions.

The characteristics of autism and mercury poisoning, derived from a review of medical literature, have been found, upon comparison, to be strikingly similar. The characteristics of both disorders are summarized in the following table and fully elucidated in the body of this document. The parallels between the two diseases are so close that it would be unreasonable to assume that the similarities occur by chance.

We claim that autism is a form of mercury poisoning, based on similarities of characteristics and on the known exposure to mercury of the majority of US children. The exposure route is childhood vaccines, most of which contain thimerosal, a preservative comprised of 50% ethylmercury by weight. The amount of mercury a typical child under two years receives from vaccinations equates to 237.5 micrograms, or 3.53 x 1017 molecules (353,000,000,000,000,000 molecules), most of which is not excreted and goes directly to the brain. The amount is known to exceed Federal safety standards, but is still considered a “low” level, such that only a small percentage of exposed individuals will exhibit signs of toxicity.  Affected individuals are those genetically prone to mercury sensitivity, which is consistent with the observed high heritability rate of autism.  Furthermore, the timing of mercury exposure via vaccines coincides with the emergence of autistic symptoms. Moreover, mercury has been detected in urine, hair, and blood samples from autistic children, and parental reports, though limited at this date, indicate significant improvement in symptoms with administration of standard heavy metal chelators. Thus, the four agreed-upon criteria used by clinicians to diagnose mercury poisoning – i.e., observable symptoms, known exposure at the time of symptom onset, detectable levels in biologic samples, and improvement with chelation - have been met for autism.

The phenotypic expression of mercury poisoning varies by a host of factors – including type of mercury given, method of administration, rate and level of dose, individual genotype, and age of patient – so that each variation in factors has created in the past a slightly different manifestation of the disease – Mad Hatter’s disease, Minamata disease, and acrodynia, for example.  The pathology arising from the set of mercury-related variables involved in autism – intermittent bolus doses of ethylmercury injected into genetically susceptible infants and toddlers – has never been reported before in medical literature. Thus we argue that autism represents a unique form of mercury poisoning not heretofore described. Our findings have widespread implications for the affected population of autistic individuals, for other unexplained disorders with symptoms similar to heavy metal intoxication, and for childhood vaccination programs.

  Summary Comparison of Characteristics

of Autism & Mercury Poisoning  

 
Mercury Poisoning

Autism

Psychiatric

Social deficits, shyness, social withdrawal

Social deficits, social withdrawal, shyness

Disturbances

Depression, mood swings; mask face

Depressive traits, mood swings; flat affect

 

Anxiety

Anxiety

 

Schizoid tendencies, OCD traits

Schizophrenic & OCD traits; repetitiveness

 

Lacks eye contact, hesitant to engage others

Lack of eye contact, avoids conversation

 

Irrational fears

Irrational fears

 

Irritability, aggression, temper tantrums

Irritability, aggression, temper tantrums

 

Impaired face recognition

Impaired face recognition

 

 

 

Speech,

Loss of speech, failure to develop speech

Delayed language, failure to develop speech

Language &

Dysarthria; articulation problems

Dysarthria; articulation problems

Hearing

Speech comprehension deficits

Speech comprehension deficits

Deficits

Verbalizing & word retrieval problems

Echolalia; word use & pragmatic errors

 

Sound sensitivity

Sound sensitivity

 

Hearing loss; deafness in very high doses

Mild to profound hearing loss

 

Poor performance on language IQ tests

Poor performance on verbal IQ tests

 

 

 

Sensory

Abnormal sensation in mouth & extremities

Abnormal sensation in mouth & extremities

Abnormalities

Sound sensitivity

Sound sensitivity

 

Abnormal touch sensations; touch aversion

Abnormal touch sensations; touch aversion

 

Vestibular abnormalities

Vestibular abnormalities

 

 

 

Motor Disorders

Involuntary jerking movements - arm flapping, ankle jerks, myoclonal jerks, choreiform movements, circling, rocking

Stereotyped movements - arm flapping, jumping, circling, spinning, rocking; myoclonal jerks; choreiform movements

 

Deficits in eye-hand coordination; limb apraxia; intention tremors

Poor eye-hand coordination; limb apraxia; problems with intentional movements

 

Gait impairment; ataxia – from incoordination & clumsiness to inability to walk, stand, or sit; loss of motor control

Abnormal gait and posture, clumsiness and incoordination; difficulties sitting, lying, crawling, and walking

 

Difficulty in chewing or swallowing

Difficulty chewing or swallowing

 

Unusual postures

Unusual postures

 

 

 

Cognitive Impairments

Borderline intelligence, mental retardation - some cases reversible

Borderline intelligence, mental retardation - sometimes "recovered"

 

Poor concentration, attention, response inhibition

Poor concentration, attention, shifting attention

 

Uneven performance on IQ subtests

Uneven performance on IQ subtests

 

Verbal IQ higher than performance IQ

Verbal IQ higher than performance IQ

 

Poor short term, verbal, & auditory memory

Poor short term, auditory & verbal memory

 

Poor visual and perceptual motor skills, impairment in simple reaction time

Poor visual and perceptual motor skills, lower performance on timed tests

 

Difficulty carrying out complex commands

Difficulty carrying out multiple commands

 

Alexia (inability to comprehend the meaning of written words)

Hyperlexia (ability to decode words while lacking word comprehension)

 

Deficits in understanding abstract ideas & symbolism; degeneration of higher mental powers

Deficits in abstract thinking & symbolism, understanding other’s mental states, sequencing, planning & organizing

(ii)


Unusual

Stereotyped sniffing (rats)

Stereotyped, repetitive behaviors

Behaviors

ADHD traits

ADHD traits

 

Agitation, unprovoked crying, grimacing, staring spells

Agitation, unprovoked crying, grimacing, staring spells

 

Sleep difficulties

Sleep difficulties

 

Eating disorders, feeding problems

Eating disorders, feeding problems

 

Self injurious behavior, e.g. head banging

Self injurious behavior, e.g. head banging

 

 

 

Visual

Poor eye contact, impaired visual fixation

Poor eye contact, problems in joint attention

Impairments

“Visual impairments,” blindness, near-sightedness, decreased visual acuity

“Visual impairments”; inaccurate/slow saccades; decreased rod functioning

 

Light sensitivity, photophobia

Over-sensitivity to light

 

Blurred or hazy vision

Blurred vision

 

Constricted visual fields

Not described

 

 

 

Physical Disturbances

Increase in cerebral palsy; hyper- or hypo-tonia; abnormal reflexes; decreased muscle strength, especially upper body; incontinence; problems chewing, swallowing, salivating

Increase in cerebral palsy; hyper- or hypotonia; decreased muscle strength, especially upper body; incontinence; problems chewing and swallowing

 

Rashes, dermatitis/dry skin, itching; burning

Rashes, dermatitis, eczema, itching

 

Autonomic disturbance:  excessive sweating, poor circulation, elevated heart rate

Autonomic disturbance:  unusual sweating, poor circulation, elevated heart rate

 

 

 

Gastro-intestinal

Gastroenteritis, diarrhea; abdominal pain, constipation, “colitis”

Diarrhea, constipation, gaseousness, abdominal discomfort, colitis

Disturbances

Anorexia, weight loss, nausea, poor appetite

Anorexia; feeding problems/vomiting

 

Lesions of ileum & colon; increases gut permeability

Leaky gut syndrome

 

Inhibits dipeptidyl peptidase IV, which cleaves casomorphin

Inadequate endopeptidase enzymes needed for breakdown of casein & gluten

 

 

 

Abnormal Biochemistry

Ties up -SH groups; blocks sulfate transporter in intestines, kidneys

Low sulfate levels

 

Has special affinity for purines & pyrimidines

Purine & pyrimidine metabolism errors lead to autistic features

 

Reduces availability of glutathione, needed in cells & liver to detoxify heavy metals

Low levels of glutathione; decreased ability of liver to detoxify heavy metals

 

Causes significant reduction in  glutathione peroxidase and glutathione reductase

Abnormal glutathione peroxidase activities in erythrocytes

 

Disrupts mitochondrial activities, especially in brain

Mitochondrial dysfunction, especially in brain

 

 

 

Immune Dysfunction

Sensitivity due to allergic or autoimmune reactions; sensitive individuals more likely to have allergies, asthma, autoimmune-like symptoms, especially rheumatoid-like ones

More likely to have allergies and asthma; familial presence of autoimmune diseases, especially rheumatoid arthritis; IgA deficiencies

 

Can produce an immune response in CNS

On-going immune response in CNS

 

Causes brain/MBP autoantibodies 

Brain/MBP autoantibodies present

 

Causes overproduction of Th2 subset; kills/inhibits lymphocytes, T-cells, and monocytes; decreases NK T-cell activity; induces or suppresses IFNg & IL-2

Skewed immune-cell subset in the Th2 direction; decreased responses to T-cell mitogens; reduced NK T-cell function; increased IFNg & IL-12

CNS Structural Pathology

Selectively targets brain areas unable to detoxify or reduce Hg-induced oxidative stress

Specific areas of brain pathology; many functions spared

 

Damage to Purkinje and granular cells

Damage to Purkinje and granular cells

 

Accummulates in amygdala and hippocampus

Pathology in amygdala and hippocampus

 

Causes abnormal neuronal cytoarchitecture; disrupts neuronal migration & cell division; reduces NCAMs

Neuronal disorganization; increased neuronal cell replication, increased glial cells; depressed expression of NCAMs

 

Progressive microcephaly

Progressive microcephaly and macrocephaly

 

Brain stem defects in some cases

Brain stem defects in some cases

 

 

 

Abnormalities in Neuro-chemistry

Prevents presynaptic serotonin release & inhibits serotonin transport; causes calcium disruptions

Decreased serotonin synthesis in children;  abnormal calcium metabolism

 

Alters dopamine systems; peroxidine deficiency in rats resembles mercurialism in humans

Possibly high or low dopamine levels; positive response to peroxidine (lowers dopamine levels)

 

Elevates epinephrine & norepinephrine levels by blocking enzyme that degrades epinephrine

Elevated norepinephrine and epinephrine

 

Elevates glutamate

Elevated glutamate and aspartate

 

Leads to cortical acetylcholine deficiency; increases muscarinic receptor density in hippocampus & cerebellum

Cortical acetylcholine deficiency; reduced muscarinic receptor binding in hippocampus

 

Causes demyelating neuropathy

Demyelation in brain

 

 

 

EEG Abnormalities/

Causes abnormal EEGs, epileptiform activity

Abnormal EEGs, epileptiform activity

Epilepsy

Causes seizures, convulsions

Seizures; epilepsy

 

Causes subtle, low amplitude seizure activity

Subtle, low amplitude seizure activities

 

 

 

Population

Effects more males than females

Male:female ratio estimated at 4:1

Characteristics

At low doses, only affects those genetically susceptible

High heritability - concordance for MZ twins is 90%

 

First added to childhood vaccines in 1930s

First "discovered" among children born in 1930s

 

Exposure levels steadily increased since 1930s with rate of vaccination, number of vaccines

Prevalence of autism has steadily increased from 1 in 2000 (1940s) to 1 in 500 (1990s)

  

Exposure occurs at 0 - 15 months; clinical silent stage means symptom emergence delayed; symptoms emerge gradually, starting with movement & sensation

Symptoms emerge from 4 months to 2 years old; symptoms emerge gradually, starting with movement & sensation

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